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Phenobarbital lowers the plasma levels of dicumarol (name Earlier made use of: bishydroxycoumarin) and triggers a decrease in anticoagulant activity as calculated because of the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing improved metabolism and lowered anticoagulant response of oral anticoagulants (e.When on an out
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Pentobarbital was used in a U.S. execution for the first time in December 2010 in Oklahoma, as part of a three-drug protocol.[14] In March 2011 pentobarbital was useful for the first time as the sole drug in a U.S. execution, in Ohio. Considering the fact that then several states and also the federal government have used pentobarbital for lethal in
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